M Julia Maristany, Anne Aguirre Gonzalez ... Jerelle A Joseph
Phase diagrams for 140 variants of prion-like low-complexity domains are computed to establish scaling laws that quantify the impact of amino acid mutations on the thermodynamic stability of condensates.
Further evidence in support of a new amyloid-independent hypothesis for the pathogenesis of Alzheimer's disease is provided, with an expanded set of Alzheimer-causing mutations in the protease that produces amyloid.
Marina Padilha, Victor Nahuel Keller ... Gilberto Kac
A panel of serum biomarkers, including dietary and microbial-derived metabolites related to the gut-brain axis, were identified as potential for tracking children at risk of early childhood developmental delays.