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Page 2 of 271
Biochemistry and Chemical Biology
Identification of human TERT elements necessary for telomerase recruitment to telomeres
Jens C Schmidt et al.
The TEN-domain of human telomerase mediates the direct interaction with TPP1 to drive telomerase recruitment to telomeres.
PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in
Claire E Richardson et al.
The protein PTRN-1 anchors microtubules in neuronal branches to promote proper neuron morphology and function in
Replication Study: Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
Hongyan Wang et al.
Editors' Summary: This Replication Study did not reproduce those experiments in the original paper that it attempted to reproduce.
Registered report: Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
Mitch Phelps et al.
α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism
Amin Khalifeh-Soltani et al.
The milk protein Mfge8 promotes fat uptake and slows gastrointestinal motility to optimize nutrient absorption.
Rac1-mediated membrane raft localization of PI3K/p110β is required for its activation by GPCRs or PTEN loss
Onur Cizmecioglu et al.
A unique two-step mechanism of plasma membrane recruitment and activation governs G-protein-coupled receptor mediated PI3K signaling.
Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron
Nils O Lindström et al.
The patterning of the nephron is driven by a gradient in the activity of β-catenin and further defined by a network of BMP, PTEN and NOTCH signalling.
NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in
Shaohe Wang et al.
ninein homolog NOCA-1 is important for the assembly of non-centrosomal microtubule arrays required for embryo production, nuclear positioning and larval development.
Stem Cells and Regenerative Medicine
Chromosomes and Gene Expression
Polycomb enables primitive endoderm lineage priming in embryonic stem cells
Robert S Illingworth et al.
Polycomb enables lineage priming in mouse embryonic stem cells by establishing a barrier to commitment.
Humans can efficiently look for but not select multiple visual objects
Eduard Ort et al.
During search for multiple targets, individuals can efficiently prepare to select multiple target objects simultaneously, but the actual selection of those objects from the sensory input is limited.
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