12 results found
    1. Developmental Biology
    2. Neuroscience

    Cis and trans RET signaling control the survival and central projection growth of rapidly adapting mechanoreceptors

    Michael S Fleming, Anna Vysochan ... Wenqin Luo
    Cis and trans activation of the receptor tyrosine kinase RET lead to similar biological outcomes in rapidly adapting mechanoreceptors in vivo.
    1. Neuroscience

    A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites

    Nan Jiang, Jeffrey P Rasmussen ... Jay Z Parrish
    Epidermal cells in vertebrates and invertebrates ensheath portions of somatosensory neurons via a conserved morphogenetic mechanism, and this ensheathment regulates morphogenesis and function of Drosophila nociceptive neurons.
    1. Developmental Biology
    2. Neuroscience

    Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2

    Simon Desiderio, Frederick Schwaller ... Frederic Marmigere
    Combining mouse genetic, behavioral, and electrophysiological approaches revealed that a transcription factor is required to shape touch neurons' distal projections in the skin while dispensable for their survival and specification.
    1. Neuroscience

    Intrinsic mechanical sensitivity of mammalian auditory neurons as a contributor to sound-driven neural activity

    Maria C Perez-Flores, Eric Verschooten ... Ebenezer N Yamoah
    In vitro and in vivo physiological analyses reveal that mammalian auditory neuron intrinsic mechanical sensitivity contributes to sound-evoked activity and explains other previously unexplained auditory neuron features.
    1. Neuroscience

    Perception of microstimulation frequency in human somatosensory cortex

    Christopher L Hughes, Sharlene N Flesher ... Robert A Gaunt
    Increasing microstimulation frequency in some regions of the human somatosensory cortex decreased the perceived intensity and evoked specific percepts, providing insight into cortical organization and sensory feedback approaches for brain–computer interfaces.
    1. Neuroscience

    Unsupervised learning of haptic material properties

    Anna Metzger, Matteo Toscani
    Perceptual haptic representation of materials emerges from unsupervised learning as a consequence of efficient encoding of the physical signals at the input of tactile sensory system.
    1. Developmental Biology
    2. Neuroscience

    Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling

    Hao Wu, John Williams, Jeremy Nathans
    The first survey of the complete morphologies of nerve endings in the skin of mice has revealed enormous structural diversity.
    1. Neuroscience

    Memory at your fingertips: how viscoelasticity affects tactile neuron signaling

    Hannes P. Saal, Ingvars Birznieks, Roland S. Johansson
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn

    Kelly M Smith, Tyler J Browne ... Brett A Graham
    A signal amplifier network that transmits mechanical pain is delineated through characterising an excitatory interneuron population in the spinal cord dorsal horn and defining the postsynaptic populations they regulate.
    1. Computational and Systems Biology
    2. Neuroscience

    Rate and timing of cortical responses driven by separate sensory channels

    Hannes P Saal, Michael A Harvey, Sliman J Bensmaia
    Signals from different tactile submodalities are integrated optimally to culminate in cortical responses whose rate and timing conveys stimulus information.

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