3 results found
    1. Stem Cells and Regenerative Medicine

    Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity

    John B Lees-Shepard et al.
    Daily palovarotene treatment reduces pathogenic expansion of fibro/adipogenic progenitors but results in long bone growth plate loss and overgrowths of synovial cartilage in juvenile mice.
    1. Stem Cells and Regenerative Medicine

    Response to comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'

    David J Goldhamer, John B Lees-Shepard
    We respond to concerns expressed by Pacifici and Shore (2019) about our recent paper (Lees-Shepard et al., 2018a).
    1. Stem Cells and Regenerative Medicine

    Comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'

    Maurizio Pacifici, Eileen M Shore
    We are writing to communicate our concerns regarding the recently published study by Lees-Shepard et al. (2018).

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