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Myostatin signaling governs neonatal longitudinal muscle growth and neuromuscular contractures in a sex-dependent manner, identifying a potential avenue for contracture treatment and underscoring the need to consider sex as a biological variable in the pathophysiology of acquired neuromuscular disorders.

DNA lesions formed by alkylating agents trigger double-strand breaks, in the absence of replication, by the action of MMR and BER at nearby O-alkyl and N-alkyl adducts, respectively.

Metabolic stress-induced activation of the JNK3 protein regulates excitatory transmission onto AgRP neurons to regulate food consumption.

A previously uncharacterized type of bivalent chromatin plays an important role controlling the timely induction of genes involved in making a potent defense metabolite upon a pathogen signal in Arabidopsis.

Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.

Studies of EMRE, one of the four essential protein subunits in the mitochondrial calcium uniporter complex that regulates calcium ion levels in mitochondria, reveal new details about the physical interactions between the subunits.

CAMSAP2 co-condensates with αβ-tubulin to induce microtubule nucleation and growth, serving as a microtubule-organizing centre for non-centrosomal microtubules.

An interaction between two proteins enables the spindle—the structure that segregates chromosome pairs during mitosis—to change size as cells divide.

In Caenorhabditis elegans, dendrites establish their unique microtubule polarity by localizing an organizing center behind the growing tip.

Early oocyte development takes place in germline cysts and is strikingly conserved from Drosophila to mouse, reflecting common mechanisms that may help reverse aging and specify oocyte and early embryo polarity.