Odessa R Yabut, Jessica Arela ... Samuel J Pleasure
Mice with Suppressor of Fused mutations have aberrant cerebellar granule cell proliferation accompanied by ectopic expression of an FGF ligand, also expressed in infantile medulloblastoma patients.
Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in fibrotic fibroblasts.
Exploiting the power of the Fshr reporter, the first comprehensive genetic record of the spatial distribution of FSHR expression offers prospects for extensive exploration of FSH-FSHR biology.