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Airborne PM2.5 exposure triggers oxidative stress and mitochondrial apoptosis in placental trophoblast cells via the KLF9/CYP1A1 transcriptional axis, ultimately leading to adverse pregnancy outcomes.

Cells control signal circulation to set the frequency of information transmitted over tissue scales.

The foundations of genomic complexity in multicellular animals have deep roots in their unicellular prehistory, both in terms of innovations in gene content, as well as the evolutionary dynamics of genome architecture.

Impairing TDP-43 RNA-binding capacity through a single acetylation-mimic mutation alters TDP-43 function and recapitulates biochemical, molecular, and behavioral features of sporadic TDP-43 proteinopathies, thus providing opportunities for new research into pathogenic mechanisms and therapeutic interventions.

The transcriptomic and epigenetic landscapes of developing human articular and growth plate cartilage reveal putative gene regulatory networks governing lineage commitment and tissue homeostasis.

A novel form of self-fertility evolved in Cryptococcus depauperatus, a close relative to the human pathogenic Cryptococcus species, in which sexual development is attained by self-signaling of a cognate pheromone and pheromone-receptor pair.

In the injured sciatic nerve, blood-derived monocytes and macrophages eat dying leukocytes, thereby contributing to nerve debridement and inflammation resolution, and this correlates with neuronal regeneration.

A comparison of different bioimage analysis pipelines reveals how deep learning can be used for automatized and reliable analysis of fluorescent features in biological datasets.