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Page 2 of 238
    1. Plant Biology

    Landscape genomic prediction for restoration of a Eucalyptus foundation species under climate change

    Megan Ann Supple, Jason G Bragg ... Justin O Borevitz
    Empirical patterns of genomic and phenotypic variation across the landscape are used to develop a predictive model that will help build resilient ecological communities.
    1. Evolutionary Biology

    Mammalian forelimb evolution is driven by uneven proximal-to-distal morphological diversity

    Priscila S Rothier, Anne-Claire Fabre ... Anthony Herrel
    The diversification of hand bones in mammals was much more dynamic than those of the proximal and intermediate forearm, involving higher morphological diversity, stronger integration, and greater evolutionary lability at distal structures.
    1. Evolutionary Biology

    Phenotypic plasticity as a mechanism of cave colonization and adaptation

    Helena Bilandžija, Breanna Hollifield ... William Jeffery
    Astyanax mexicanus surface-dwelling fish exposed to complete darkness develop many traits resembling cavefish adaptations by phenotypic plasticity in a single generation.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Effects of an IgE receptor polymorphism acting on immunity, susceptibility to infection, and reproduction in a wild rodent

    Klara M Wanelik, Mike Begon ... Steve Paterson
    Genetic variation can have multiple effects on different phenotypic traits in organisms living in the natural environment.
    1. Evolutionary Biology

    Selection and the direction of phenotypic evolution

    François Mallard, Bruno Afonso, Henrique Teotónio
    Predicting multivariate phenotypic evolution.
    1. Genetics and Genomics

    Genetic Variation: Searching for solutions to the missing heritability problem

    Luisa F Pallares
    Rare genetic variants in yeast explain a large amount of phenotypic variation in a complex trait like growth.
    Version of Record
    Insight
    1. Genetics and Genomics

    Relating multivariate shapes to genescapes using phenotype-biological process associations for craniofacial shape

    Jose D Aponte, David C Katz ... Benedikt Hallgrímsson
    Multivariate genotype-phenotype mapping enables quantification of pathway and process-level effects on complex phenotypes and predicts phenotypic effects of novel mutations.
    1. Developmental Biology
    2. Evolutionary Biology

    Developmental Variability: Exerting an influence on evolution

    Charles C Roseman
    Experiments on mice have shown that developmental processes are influencing the generation of phenotypic variation in a way that shapes evolution.
    Version of Record
    Insight
    1. Genetics and Genomics

    Genetic architecture of natural variation of cardiac performance from flies to humans

    Saswati Saha, Lionel Spinelli ... Laurent Perrin
    Comprehensive genome-wide associations studies in flies identify new genes and pathways critical for heart development and function and display relevant overlap with human genetic risks related to cardiac performance.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Hybridization alters the shape of the genotypic fitness landscape, increasing access to novel fitness peaks during adaptive radiation

    Austin H Patton, Emilie J Richards ... Christopher H Martin
    Hybridization not only generates genetic diversity, but this diversity can alter the shape of the fitness landscape, changing which genotypic combinations are favored by natural selection and which accessible genotypic paths lead to novel fitness peaks.