Receptor recognition of antimicrobial peptides is important for Salmonellae to survive inside macrophages and cause disease.

The phosphate starvation response network in a commensal yeast evolved to expand its downstream targets via changes in the main transcription factor's dependence on its co-activator, potentially altering the physiological response.

Visual, parietal, and frontal motor cortices play distinct and necessary roles in mapping sensory features to future motor action.

Mutations along the signaling pathway of the E. coli sensor histidine kinase PhoQ alter signal gain and ligand-sensitivity by altering thermodynamic allosteric coupling between domains.

The integration of multi-nucleosome configuration data with histone turnover and new chromatin accessibility data by systematically investigated 'regulated on-off-slide' models reveals promoter state transitions regulated by just one assembly process.

In a stress-specific manner, Mycobacterium tuberculosis PhoP regulates Rv0805 phosphodiesterase expression to control cAMP level and contributes to intracellular survival of the bacilli.

Analysis of inositol pyrophosphate dynamics upon inorganic phosphate (P_i) starvation identifies 1,5-IP₈ as the inositol pyrophosphate isomer signaling P_i sufficiency to the SPX domain of Pho81 that controls the transcriptional P_i starvation program.

Molecular architecture of the secreted NS1 dimer from dengue virus infection in complex with a high density lipoprotein particle.

The transcription factor (TF)-binding specificities of Pseudomonas aeruginosa allow us to predict virulence-associated TFs and their target genes, which will facilitate to find effective treatment and prevention for its associated diseases.

Mutations in gene regulatory proteins set the stage for the evolution of antimicrobial resistance by shifting the fitness landscape of resistance-conferring mutations.