16 results found
    1. Genetics and Genomics

    The rise and fall of the Phytophthora infestans lineage that triggered the Irish potato famine

    Kentaro Yoshida et al.
    The strain of Phytophthora infestans that caused the Great Famine in the late 1840s was caused by a single genotype that is distinct from, but closely related to, the most prevalent modern genotype.
    1. Cell Biology
    2. Plant Biology

    Host autophagy machinery is diverted to the pathogen interface to mediate focal defense responses against the Irish potato famine pathogen

    Yasin F Dagdas et al.
    Defense-related selective autophagy mediated by the antimicrobial autophagy cargo receptor NBR1/Joka2 is diverted to pathogen penetration sites to restrict plant colonization by the oomycete pathogen Phytophthora infestans.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Plant Disease: Autophagy under attack

    Paul de Figueiredo, Marty Dickman
    Insight
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    1. Genetics and Genomics

    Genomics: The early days of late blight

    Paul RJ Birch, David EL Cooke
    Insight
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    1. Microbiology and Infectious Disease
    2. Plant Biology

    An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor

    Yasin F Dagdas et al.
    A plant pathogen effector evolved a short linear motif to subvert autophagic defenses by antagonising a host cargo receptor.
    1. Plant Biology

    Pathogen effectors and plant immunity determine specialization of the blast fungus to rice subspecies

    Jingjing Liao et al.
    Specialized fungal pathogen populations infect rice varieties with contrasting immune systems co-cultivated in a traditional agro-system, indicating the relevance of crop diversity to restricting epidemics in the landscape.
    1. Genetics and Genomics
    2. Plant Biology

    Evidence for suppression of immunity as a driver for genomic introgressions and host range expansion in races of Albugo candida, a generalist parasite

    Mark McMullan et al.
    Hybridization and introgression blur species boundaries and broaden genetic diversity available for adaptation; and widespread introgression underpins the evolution of races of the generalist pathogen Albugo candida that specialise on different host plant species.
    1. Plant Biology

    Autophagy functions as an antiviral mechanism against geminiviruses in plants

    Yakupjan Haxim et al.
    Plant autophagy contributes to antiviral defense against geminiviruses by targeting one or more viral proteins for degradation.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation

    Franziska Bleichert et al.
    Electron microscopy uncovers the structure of the origin recognition complex (ORC) in metazoans, and reveals how mutations in the ORC6 subunit lead to Meier-Gorlin syndrome in humans.

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