553 results found
    1. Cell Biology
    2. Developmental Biology

    Telophase correction refines division orientation in stratified epithelia

    Kendall J Lough et al.
    Telophase reorientation corrects errors in spindle orientation that persist after imprecise initial spindle positioning during early mitosis, and contributes to balancing self-renewal with differentiation during epidermal development.
    1. Stem Cells and Regenerative Medicine

    The follicle epithelium in the Drosophila ovary is maintained by a small number of stem cells

    Jocelyne Fadiga, Todd G Nystul
    Just 2-4 follicle stem cells maintain each follicle epithelium in the Drosophila ovary, and they reside within a single ring at the anterior edge of the tissue.
    1. Cell Biology
    2. Developmental Biology

    Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth

    Steve Dos-Santos Carvalho et al.
    The core PCP protein acts as a internal brake to neuronal outgrowth.
    1. Neuroscience

    Amyloid and tau accumulate across distinct spatial networks and are differentially associated with brain connectivity

    Joana B Pereira et al.
    The amyloid patterns overlap with the default-mode network, whereas the tau patterns overlap with distinct functional networks and are associated with a loss of anatomical connectivity and multiple cognitive functions.
    1. Evolutionary Biology
    2. Structural Biology and Molecular Biophysics

    Structure of a mitochondrial ATP synthase with bound native cardiolipin

    Alexander Mühleip et al.
    The atomic model of a mitochondrial ATP synthase dimer underlies functions of its specific protein constituents and boundary cardiolipins.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity

    Keisuke Kitakaze et al.
    Cell-based high-throughput screening identifies IBT21 as a chemical chaperone, that inhibits ER protein aggregation and prevents the cell death caused by a proteotoxin, the aggregation-prone prion protein.
    1. Cell Biology
    2. Immunology and Inflammation

    B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments

    Sophie I Roper et al.
    Two modes of actin polymerization, branched and linear, cooperate in B cells to extract antigens from surfaces of presenting cells.
    1. Human Biology and Medicine

    Straightjacket/α2δ3 deregulation is associated with cardiac conduction defects in myotonic dystrophy type 1

    Emilie Auxerre-Plantié et al.
    Drosophila DM1 models suggest that elevated cardiac expression of straightjacket/α2δ3, a regulatory subunit of voltage-gated calcium channel, contributes to cardiac conduction defects in DM1.
    1. Genetics and Genomics

    Novel genetic loci affecting facial shape variation in humans

    Ziyi Xiong et al.
    A comprehensive genome scan of 18,000 multi-ethnic individuals with 3-dimensional facial images highlighted multiple face-associated genetic loci for which regulatory activities in human neural cells were established.

Refine your results by:

Type
Research categories