517 results found
  1. February 2016

    Episode 27: February 2016

    In this episode we hear about midnight snacking, X-ray imaging of fossils, hummingbirds, monkeys gambling and axolotls regenerating.
  2. September 2013

    Episode 4: September 2013

    In this episode we hear about how flatworms regenerate, the evolution of photosynthesis, social interactions between mice, the properties of undead cells, and how steroids and genes interact.
  3. Episode 3: August 2013

    Episode 3: August 2013

    In this episode we hear about the cocktail party effect, the role of psuedogene RNA in the immune response, the genetic origins of a common form of blindness, the flu vaccine, and the origins of schistosomiasis.
  4. April 2014

    Episode 11: April 2014

    In this episode we hear about neuropathic pain, gene therapy, insulin production, aging in worms, and how flatworms grow new body parts.
    1. Computational and Systems Biology
    2. Developmental Biology

    Elastic force restricts growth of the murine utricle

    Ksenia Gnedeva et al.
    Computational modeling and molecular-biological analysis reveal the role of mechanical force and downstream Yap signaling in growth control during the development and regeneration of sensory epithelium of the inner ear.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Two-step membrane binding by the bacterial SRP receptor enable efficient and accurate Co-translational protein targeting

    Yu-Hsien Hwang Fu et al.
    Single molecule microscopy combined with biochemical analyses show that a two-step lipid-binding mechanism of the SRP receptor balances the trade-off between speed and specificity during co-translational protein targeting.
    1. Structural Biology and Molecular Biophysics
    2. Plant Biology

    Kinetics of the LOV domain of ZEITLUPE determine its circadian function in Arabidopsis

    Ashutosh Pudasaini et al.
    In the plant circadian clock photoreceptor ZEITLUPE, evolutionarily selected residues distinguish photocycle kinetics and allosteric signal transduction pathways to permit proper circadian timing.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction

    Gurunathan Laxmikanthan et al.
    The structure of a multi-protein DNA recombination reaction intermediate reveals how regulation is achieved by protein-mediated DNA wrapping around a core enzyme-substrate complex.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling

    Ariane Briegel et al.
    Bacterial cytoplasmic chemoreceptors assemble into a sandwich of two hexagonally packed arrays.
    1. Immunology and Inflammation
    2. Physics of Living Systems

    Light-based tuning of ligand half-life supports kinetic proofreading model of T cell signaling

    Doug K Tischer, Orion David Weiner
    Direct control of ligand binding half-life with light shows that lifetime strongly affects T cell signaling.

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