A new high-resolution approach to probing tooth chemistry shows real potential to uncover changing rainfall patterns and environmental conditions during human prehistory.

Stdpopsim, a framework for generating realistic chromosome-scale simulations, is expanded to facilitate simulations for non-model species, resulting in insights into how such simulations should be designed.

A paternal bias in germline mutation is seen throughout amniotes and may be explained by sex differences in DNA damage and repair after primordial germ cell specification.

The human-like joint proportions of Australopithecus afarensis evolved independently, making 'Lucy' and her kind the earliest known evolutionary experiment in obligate bipedalism.

A genetic basis underlying cell resilience against metabolic stress in cells of a hibernator, Arctic ground squirrels, has been discovered.

Mutations in the TRIM5α retrovirus-binding interface frequently improve but rarely disrupt retroviral restriction.

The stdpopsim library, a community-driven open source project, is presented which provides easy access to a standard catalog of published simulation models for population genetics aimed at field-wide standardization.

Skd3 (human ClpB) is a potent ATP-dependent mitochondrial protein disaggregase that is activated by the rhomboid protease, PARL, and inactivated by MGCA7-linked mutations.