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    1. Immunology and Inflammation

    Genetic timestamping of plasma cells in vivo reveals tissue-specific homeostatic population turnover

    An Qi Xu, Rita R Barbosa, Dinis Pedro Calado
    A new system to genetically label and manipulate plasma cells in vivo in their microenvironment resolves current technical limitations and reveals tissue-specific homeostatic population turnover.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High-quality carnivoran genomes from roadkill samples enable comparative species delineation in aardwolf and bat-eared fox

    Rémi Allio, Marie-Ka Tilak ... Frédéric Delsuc
    High-quality genomes can be obtained from roadkill samples and used in population genomics for species delimitation with conservation implications.
    1. Evolutionary Biology
    2. Genetics and Genomics

    On the limits of fitting complex models of population history to f-statistics

    Robert Maier, Pavel Flegontov ... David Reich
    Many published findings about population history that rely on inference of admixture graph models fitted to f-statistics are not robust since the method is generally inappropriate for extracting new information about population history.
    1. Genetics and Genomics
    2. Plant Biology

    DNA methylation in Arabidopsis has a genetic basis and shows evidence of local adaptation

    Manu J Dubin, Pei Zhang ... Magnus Nordborg
    The adaptation of Arabidopsis plants to the local environment is linked to DNA methylation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Demographic reconstruction from ancient DNA supports rapid extinction of the great auk

    Jessica E Thomas, Gary R Carvalho ... Michael Knapp
    Reconstruction of great auk population dynamics suggests that hunting pressure alone could have been responsible for their extinction, demonstrating that even abundant, widespread species can be vulnerable to intense exploitation.
    1. Genetics and Genomics

    The genetic basis for ecological adaptation of the Atlantic herring revealed by genome sequencing

    Alvaro Martinez Barrio, Sangeet Lamichhaney ... Leif Andersson
    Whole genome sequencing of 19 populations of Atlantic and Baltic herring reveals hundreds of individual loci underlying adaptation to a low salinity niche or timing of reproduction.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    The Aquilegia genome provides insight into adaptive radiation and reveals an extraordinarily polymorphic chromosome with a unique history

    Danièle L Filiault, Evangeline S Ballerini ... Magnus Nordborg
    The evolution columbine genus involved frequent mixing between incipient species, and one chromosome appears to have taken its own path.
    1. Genetics and Genomics

    Association analyses of host genetics, root-colonizing microbes, and plant phenotypes under different nitrogen conditions in maize

    Michael A Meier, Gen Xu ... Jinliang Yang
    Comprehensive analyses of host genetics, root-associated microbiomes, and plant phenotypes under two nitrogen treatments reveals host genetic control of microbe abundance which, in turn, affects plant performance.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1

    Colin LaMont, Jakub Otwinowski ... Armita Nourmohammad
    Computational evolutionary model to predict the efficacy of broadly neutralizing antibodies (bNAbs) in suppressing HIV and to design optimal combination therapy with bNAbs.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Recurrent evolution of high virulence in isolated populations of a DNA virus

    Tom Hill, Robert L Unckless
    The same host–virus interactions can evolve multiple times in nature, due to the high effective mutation rate of viruses, and provide interesting systems of study.