85 results found
    1. Evolutionary Biology
    2. Genetics and Genomics

    The distribution of fitness effects among synonymous mutations in a gene under directional selection

    Eleonore Lebeuf-Taylor et al.
    Synonymous mutations can have highly variable fitness effects stemming from changes in transcription, some of which contribute to adaptation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Predicting mutational routes to new adaptive phenotypes

    Peter A Lind et al.
    A combination of genetics, experimental evolution and mathematical modelling defines information necessary to predict the outcome of short-term adaptive evolution.
    1. Evolutionary Biology

    Experimental evolution reveals hidden diversity in evolutionary pathways

    Peter A Lind et al.
    Genetic architecture governs the evolvability of adaptive paths providing a framework for evolutionary forecasting.
    1. Microbiology and Infectious Disease

    An orphan cbb3-type cytochrome oxidase subunit supports Pseudomonas aeruginosa biofilm growth and virulence

    Jeanyoung Jo et al.
    During growth in biofilms and host infection, the opportunistic pathogen Pseudomonas aeruginosa employs respiratory heterocomplexes that support extracellular electron shuttling and pathogenicity.
    1. Microbiology and Infectious Disease

    Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli

    Toon Swings et al.
    Population mutation rates are highly flexible and evolvable under extreme stress conditions, matching changes in selective pressure to avoid extinction of the entire population.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Novel mechanism of metabolic co-regulation coordinates the biosynthesis of secondary metabolites in Pseudomonas protegens

    Qing Yan et al.
    The production of two secondary metabolites is co-regulated in a bacterium via an intermediate in one pathway that is converted into signals to activate the second pathway.
    1. Structural Biology and Molecular Biophysics

    Structure of a type IV pilus machinery in the open and closed state

    Vicki AM Gold et al.
    Electron cryo-tomography reveals a huge conformational change in the secretin domain of the type IV pilus machinery that occurs when the channel opens for pilus extrusion.
    1. Physics of Living Systems

    Shared behavioral mechanisms underlie C. elegans aggregation and swarming

    Siyu Serena Ding et al.
    Two seemingly distinct behaviors in social C. elegans worms, namely aggregating into groups and swarming over food, are driven by the same underlying mechanisms.
    1. Cell Biology
    2. Plant Biology

    Arabidopsis heterotrimeric G proteins regulate immunity by directly coupling to the FLS2 receptor

    Xiangxiu Liang et al.
    Heterotrimeric G proteins are coupled to and regulate plant receptor signaling, which allows optimum immune activation and enhances the production of reactive oxygen species.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    Avoidance of stochastic RNA interactions can be harnessed to control protein expression levels in bacteria and archaea

    Sinan Uğur Umu et al.
    Stochastic mRNA and non-coding RNA hybridisation has a major impact on protein expression.

Refine your results by:

Type
Research categories