357 results found
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    The NTP generating activity of pyruvate kinase II is critical for apicoplast maintenance in Plasmodium falciparum

    Russell P Swift et al.
    The pyruvate kinase contained in the apicoplast organelle of malaria parasites makes the nucleotide triphosphates required for several processes including transcription of the organellar genome.
    1. Neuroscience

    Firing rate-dependent phase responses of Purkinje cells support transient oscillations

    Yunliang Zang et al.
    Computational and theoretical models show that rate adaptation of phase responses can regulate Purkinje cell outputs by forming transient oscillations in fast-spiking neurons.
    1. Biochemistry and Chemical Biology

    Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

    Sara M Nowinski et al.
    Mitochondrial fatty acid synthesis is best known for producing lipoic acid, however, longer acyl chain products regulate mitochondrial electron transport chain assembly, oxidative TCA cycle metabolism, and skeletal myoblast differentiation.
    1. Cancer Biology
    2. Human Biology and Medicine

    The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model

    Jaime N Wertman et al.
    L-mimosine and dopamine protect against cisplatin-induced oto- and nephrotoxicity in zebrafish and human cell line models.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Resource plasticity-driven carbon-nitrogen budgeting enables specialization and division of labor in a clonal community

    Sriram Varahan et al.
    Sufficient aspartate drives specialization within a microbial colony, when some cells use it to create a limited carbon-resource, while other cells consume this resource and use aspartate for nucleotide synthesis.
    1. Neuroscience

    Axonal mechanisms mediating γ-aminobutyric acid receptor type A (GABA-A) inhibition of striatal dopamine release

    Paul F Kramer et al.
    GABA-A receptors on dopamine neuron axons not only depolarize the membrane but also limit action potential propagation, an effect potentiated by positive allosteric modulators of GABA-A receptors like diazepam (Valium).
    1. Developmental Biology
    2. Neuroscience

    The role of the NMD factor UPF3B in olfactory sensory neurons

    Kun Tan et al.
    The nonsense-mediated RNA decay (NMD) branch-specific factor UPF3B influences olfactory sensory neuron cell populations, the olfactory receptor repertoire, and antimicrobial gene expression.
    1. Developmental Biology

    Polyploidy in the adult Drosophila brain

    Shyama Nandakumar et al.
    Terminally differentiated neurons and glia can re-enter the cell cycle to become polyploid in the adult fly brain, to protect cells from DNA damage-associated death.
    1. Neuroscience

    Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis

    Hirofumi Fujita et al.
    Medial cerebellar nucleus comprises five major types of excitatory projection neurons differentially connected with specific subsets of inferior olive neurons, Purkinje cells, and somatomotor, oromotor, positional-autonomic, orienting and arousal circuits.

Refine your results by:

Type
Research categories