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    1. Cell Biology
    2. Developmental Biology

    Patterned cortical tension mediated by N-cadherin controls cell geometric order in the Drosophila eye

    Eunice HoYee Chan, Pruthvi Chavadimane Shivakumar ... Pierre-François Lenne
    N-cadherin at heterotypic contacts controls the level and asymmetric localisation of Myosin-II motor, thereby influencing cell shapes and cell packing.
    1. Developmental Biology

    Coordination of cell cycle and morphogenesis during organ formation

    Jeffrey Matthew, Vishakha Vishwakarma ... SeYeon Chung
    The SP1/KLF transcription factor Huckebein controls endoreplication in the Drosophila salivary gland, ensuring proper morphogenesis during organ formation.
    1. Neuroscience

    A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites

    Nan Jiang, Jeffrey P Rasmussen ... Jay Z Parrish
    Epidermal cells in vertebrates and invertebrates ensheath portions of somatosensory neurons via a conserved morphogenetic mechanism, and this ensheathment regulates morphogenesis and function of Drosophila nociceptive neurons.
    1. Cell Biology
    2. Evolutionary Biology

    A unicellular relative of animals generates a layer of polarized cells by actomyosin-dependent cellularization

    Omaya Dudin, Andrej Ondracka ... Iñaki Ruiz-Trillo
    Cellularization in Sphaeroforma arctica generates a self-organized structure that morphologically resembles an epithelium, and is associated with tightly regulated expression of cell adhesion pathways.
    1. Developmental Biology

    MAFB drives differentiation by permitting WT1 binding to podocyte specific promoters

    Filippo M. Massa, Fariba Jian-Motamedi ... Andreas Schedl
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology

    Nanoscale architecture of the Schizosaccharomyces pombe contractile ring

    Nathan A McDonald, Abigail L Lind ... Kathleen L Gould
    Super-resolution microscopy reveals the nanoscale molecular architecture of 29 protein components of a eukaryotic contractile ring relative to the membrane.
    1. Developmental Biology

    Folded gastrulation and T48 drive the evolution of coordinated mesoderm internalization in flies

    Silvia Urbansky, Paula González Avalos ... Steffen Lemke
    Functional recapitulation of a likely evolutionary gain in gene expression shows that two genes are sufficient to switch mesoderm cell internalization from stochastic cell ingression to coordinated epithelial invagination.
    1. Cell Biology

    The metal transporter ZIP13 supplies iron into the secretory pathway in Drosophila melanogaster

    Guiran Xiao, Zhihui Wan ... Bing Zhou
    Drosophila ZIP13 (Slc39a13), a presumed zinc importer, is responsible for iron delivery to the secretory pathway.
    1. Genetics and Genomics

    Recognition of galactose by a scaffold protein recruits a transcriptional activator for the GAL regulon induction in Candida albicans

    Xun Sun, Jing Yu ... Yang Lu
    The transcriptional network for the GAL regulon induction in the pathogenic fungus Candida albicans represents an important advance in the evolution of the regulatory circuits, and would make a nice addition to the textbook version of eukaryotic gene regulation.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Snf1/AMPK promotes the formation of Kog1/Raptor-bodies to increase the activation threshold of TORC1 in budding yeast

    James E Hughes Hallett, Xiangxia Luo, Andrew P Capaldi
    The key Target of Rapamycin Complex (TORC1) component Kog1 moves into bodies during glucose starvation to limit reactivation of the complex.