The structure of the yeast RSC complex, a member of the SWI/SNF chromatin remodeling family, determined by cryo-electron microscopy, reveals a conserved structural core and the mode of nucleosome engagement.
ChAR-seq is a massively parallelized de novo RNA mapping assay, which is capable of generating hundreds to thousands of RNA-binding maps with no a priori knowledge of target RNAs.
Jolle Wolter Jolles, Matthew MG Sosna ... Iain D Couzin
Detailed tracking of live predators attacking live schools of prey reveals the crucial interplay between predator attack strategy and prey behaviour and positioning in determining the predation risk within mobile animal groups.
Small changes to the way COVID-19 vaccine side-effect rates are framed and communicated have meaningful impacts on individuals' vaccination intentions.
James J Gilchrist, Silvia N Kariuki ... Thomas N Williams
Defining the probability of bacterial disease among children with severe malaria allows the integration of bacteraemia and severe malaria genome-wide association study data, identifying a novel risk locus for invasive bacterial disease.
Greed personality trait is associated with behavioral loss aversion via the mediation of the neural loss aversion signal in the medial orbitofrontal cortex.
Height in early adulthood is an indicator that integrates across different dimensions of sustainable human development with links to health and longevity, nutrition, education and economic productivity.
Michael J Bartlett, Tammy E Steeves ... Patrice C Rosengrave
Seminal fluid harbours the as yet unknown mechanism that facilitates rapid adjustment of sperm velocity in response to changing sperm competition risk.
Yi-Jun Sheu, Risa Karakida Kawaguchi ... Bruce Stillman
The localization of Rad53 cell cycle checkpoint kinase to many gene promoters and the dynamic changes in response to replication stress suggests that the kinase may coordinate genome stability and gene expression.
Daniel Muñoz-Reyes, Levi J McClelland ... Maria Jose Sanchez-Barrena
Biochemical, biophysical, and structural approach to determine the molecular basis of the calcium-sensitive regulation of the Gα chaperone and guanine exchange factor Ric-8A by the neuronal calcium sensor NCS-1.