3,809 results found
    1. Chromosomes and Gene Expression
    2. Human Biology and Medicine

    Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma

    Ana R Grosso et al.
    Transcription beyond annotated gene boundaries expands the diversity of the cancer transcriptome with overexpressed oncogenes and RNA chimeras.
    1. Human Biology and Medicine
    2. Immunology and Inflammation

    Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema

    Ran You et al.
    The accumulation of carbon black nanoparticles in smokers' lungs causes sterile inflammation, double-strand DNA breaks and emphysema.
    1. Cell Biology
    2. Developmental Biology and Stem Cells

    Germ Granules: All about the RNA after all

    Tatjana Trcek, Ruth Lehmann
    RNA molecules cause the proteins involved in the formation of germ granules to coalesce into liquid droplets.
    Insight
    Available as:
    • HTML
    • PDF
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Chromocenters: Bundling up DNA

    Susan A Gerbi
    Structures known as chromocenters, comprising satellite DNA and proteins such as D1 or HMGA1, help to contain DNA inside the nucleus between cell divisions.
    Insight
    Available as:
    • HTML
    • PDF
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Heterochromatin: Silencing repetitive DNA

    Nahid Iglesias, Danesh Moazed
    Some RNAs in mammalian cells can help to silence the DNA they are transcribed from.
    Insight
    Available as:
    • HTML
    • PDF
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    sRNA-mediated activation of gene expression by inhibition of 5'-3’ exonucleolytic mRNA degradation

    Sylvain Durand et al.
    Small regulatory RNAs are able to modulate mRNA degradation rates by controlling access to the 5' end of mRNAs in bacteria.
    1. Chromosomes and Gene Expression

    Inter-Fork Strand Annealing causes genomic deletions during the termination of DNA replication

    Carl A Morrow et al.
    The discovery of a mechanism that causes DNA deletions during non-canonical DNA replication termination is described.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex

    Jin Young Kang et al.
    Cryo-electron microscopy structures show how coliphage HK022 Nun blocks Escherichia coli RNA polymerase translocation by mediating multiple interactions between the RNA polymerase and nucleic acids.
    1. Microbiology and Infectious Disease

    pp32 and APRIL are host cell-derived regulators of influenza virus RNA synthesis from cRNA

    Kenji Sugiyama et al.
    The host-derived factors, pp32 and APRIL, interact with influenza viral RNA polymerase to support viral genomic RNA synthesis from complementary RNA.
    1. Cell Biology
    2. Genetics and Genomics

    Rapid re-identification of human samples using portable DNA sequencing

    Sophie Zaaijer et al.
    DNA fingerprinting by portable nanopore sequencing is a novel re-identification method with applications in (clinical) laboratories and biobanks.

Refine your results by:

Type
Research categories