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    1. Biochemistry and Chemical Biology

    Allosteric mechanism of the V. vulnificus adenine riboswitch resolved by four-dimensional chemical mapping

    Siqi Tian et al.
    A new biochemical method tests whether or not the pre-existing RNA structural correlations couple small molecule binding to gene expression in a paradigmatic riboswitch.
  1. Point of View: Four erroneous beliefs thwarting more trustworthy research

    Mark Yarborough et al.
    Strategies to improve public trust in biomedical research are being hindered by a scientific mindset that stifles interest in reform.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Epigenetics: A memory of longevity

    Felicity Emerson et al.
    Worms with increased levels of the epigenetic mark H3K9me2 have a longer lifespan that can be passed down to future generations.
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    1. Microbiology and Infectious Disease

    Transcriptomics: Revisiting the genomes of herpesviruses

    Bhupesh K Prusty, Adam W Whisnant
    Combining integrative genomics and systems biology approaches has revealed new and conserved features in the genome of human herpesvirus 6.
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    1. Computational and Systems Biology

    Point of View: Data science for the scientific life cycle

    Daphne Ezer, Kirstie Whitaker
    Each stage of the scientific life cycle stands to benefit from the introduction of data science techniques.
    1. Microbiology and Infectious Disease

    Tropical Diseases: Can CRISPR help in the fight against parasitic worms?

    Paul McVeigh, Aaron G Maule
    The first reports of CRISPR/Cas9 genome editing in flatworms could usher in a new era of research on these dangerous human parasites.
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    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
  2. Plain-language Summaries of Research: An inside guide to eLife digests

    Stuart RF King et al.
    After summarizing over 2,400 articles in plain language, the eLife Features team shares what it has learnt about writing and editing for a broad audience.
  3. Research: Publication bias and the canonization of false facts

    Silas Boye Nissen et al.
    Publication bias, in which positive results are preferentially reported by authors and published by journals, can restrict the visibility of evidence against false claims and allow such claims to be canonized inappropriately as facts.