3,166 results found
  1. Picture of the bat Artibeus watsonii

    Episode 54: February 2019

    In this episode, we hear about colour vision in bats, frog vocal systems, ageing, problematic cell lines and how larger neurons could lead to a higher IQ.
  2. Episode 38: May 2017

    In this episode we hear about biofilms in bacteria, drug production, gender bias in peer review, nematode worms and how synchronising brain waves can boost memory.
  3. A seed next to a sign saying "nothing to declare"

    Episode 64: February 2020

    In this episode we hear about genetic privacy, plants with three parents, using cannabis to treat endometriosis, a new type of hearing test and how we can enjoy a cuddle.
  4. Episode 37: March 2017

    In this episode we hear about helping people with paralysis to communicate, how exposing mice to nicotine can affect their sons, scaffold-building parasites, the origins of handedness and plain-language summaries of research.
    1. Developmental Biology

    A mammalian Wnt5a–Ror2–Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis

    Kuan Zhang et al.
    Regulation of cellular properties such as ligand secretion and migratory ability through changes in the cytoskeleton mediated by a Wnt5a–Ror2–Vangl2 axis is a major determinant of alveolar formation.
    1. Neuroscience

    Kainate receptors regulate development of glutamatergic synaptic circuitry in the rodent amygdala

    Maria Ryazantseva et al.
    Glutamatergic projections from basolateral to central amygdala, implicated in neuropsychiatric disorders, develop rapidly during early postnatal period and their development is modulated via endogenously active kainate receptors.
    1. Developmental Biology
    2. Genetics and Genomics

    Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices

    Claudia Racioppi et al.
    ATAC-seq, CRISPR/Cas9 mutagenesis, reporter and gene expression assays revealed dynamic chromatin accessibility profiles governing differential gene expression during heart vs. pharyngeal muscle fate choices in the powerful chordate model Ciona.
    1. Developmental Biology

    Primary cilia deficiency in neural crest cells models anterior segment dysgenesis in mouse

    Céline Portal et al.
    Primary cilia of neural crest-derived cells mediate Indian hedgehog-induced signal transduction in the periocular mesenchyme and are required for normal anterior segment development.
    1. Computational and Systems Biology

    Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells

    Nalin Leelatian et al.
    A new automated and unsupervised algorithm, Risk Assessment Population IDentification, identifies risk-stratifying cells in single cell datasets with robust statistical and biological validation.
    1. Cell Biology
    2. Developmental Biology

    Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation

    Pieter R Norden et al.
    Genetic and molecular analyses show that FOXC1 and FOXC2 play a role in controlling lymphatic valve maintenance as key mediators of mechanotransduction to control cytoskeletal organization and RhoA/ROCK signaling.

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