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Opposing gradients of activin A and follistatin within the spiral shaped mammalian cochlea instruct the graded pattern of mechano-sensory hair cell formation.

Live cell imaging and the in vivo dissection into distinct stages, called landmarks, represents a new methodology for analyzing meiosis in Arabidopsis and likely in other species as well.

X-ray histotomography produces the first 3-dimensional images with the combined submicron resolution, centimeter fields-of-view, soft-tissue contrast, and potential throughput to enable quantitative, histopathological and centimeter-scale phenotyping for whole-organism phenomics.

To protect their food and themselves against detrimental mould fungi, the eggs of a wasp species synthesize and emit remarkable amounts of gaseous nitrogen oxides that are highly effective antimicrobials.

The major protein disulfide isomerase family member, PDIA1, is essential in beta cells of mice fed a high-fat diet to maintain glucose homeostasis, proinsulin maturation and organelle integrity.

Newly discovered interaction between fission yeast SPB and animal centriole components reveals that pericentrin not only functions as a microtubule-nucleator, but also promotes centriole assembly in animals.

Drosophila use distinct sensory mechanisms to detect and integrate the same tactile and taste information in two decision-making tasks that serve two different purposes.

An investigation into 8-oxodeoxguanosine bypass by archaeal DNA polymerases.

Proinsulin misfolding, an established cause of diabetes in patients with INS gene mutations, is now observed in normal human pancreatic islets, and rodents with genetic predisposition to type 2 diabetes.

ADAM17 is a key player in the non-canonical endocytosis pathway that is used by oncogenic papillomaviruses as it allows virus/receptor platform assembly by activation of the ERK1/2 signaling pathway.