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    1. Computational and Systems Biology
    2. Neuroscience

    The formation of the light-sensing compartment of cone photoreceptors coincides with a transcriptional switch

    Janine M Daum et al.
    Correlating changes in structure and gene expression in cone photoreceptors of mice daily, between birth and eye opening, created a resource that supports research in photoreceptor function, development, transplantation and repair.
    1. Genetics and Genomics
    2. Neuroscience

    Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes

    Yehudit Hasin-Brumshtein et al.
    In depth characterization of gene expression in the mouse hypothalamus will facilitate understanding of the molecular pathways that affect metabolic traits and discovers new genes associated with these pathways.
    1. Neuroscience

    Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain

    Julio D Perez et al.
    A subset of genes in the mouse brain show dynamically regulated and unequal expression of maternally and paternally derived variants, with implications for brain development and function.
    1. Plant Biology

    Negative regulation of ABA signaling by WRKY33 is critical for Arabidopsis immunity towards Botrytis cinerea 2100

    Shouan Liu et al.
    A genome-wide view of the gene regulatory network governed by WRKY33 has identified key targets that negatively regulate ABA biosynthesis to provide immunity against infection by a necrotrophic fungus.
    1. Neuroscience

    Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

    Fredrick E Henry et al.
    Cell type-specific transcriptomics in energy homeostasis neurons has identified hundreds of genes and multiple signaling pathways that are regulated by weight loss in mice, as well as several previously unexamined genes that can regulate appetite and body weight.
    1. Neuroscience

    Starvation promotes concerted modulation of appetitive olfactory behavior via parallel neuromodulatory circuits

    Kang I Ko et al.
    Starvation upregulates activity in certain sensory channels and downregulates it in others in what appears to be an optimization strategy that serves to increase the hedonic value of food odors.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    A global change in RNA polymerase II pausing during the Drosophila midblastula transition

    Kai Chen et al.
    The first zygotic genes are transcribed without RNA polymerase II pausing from a TATA-enriched promoter.
    1. Neuroscience

    The subiculum is a patchwork of discrete subregions

    Mark S Cembrowski et al.
    Pyramidal cells of the subiculum, a major output cell type of the hippocampus, can be deconstructed into distinct subtypes that exhibit a patchwork-like organization in space.
    1. Developmental Biology
    2. Neuroscience

    Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1

    Hsin-I Jen et al.
    The mammalian utricle can better regenerate hair cells compared to the cochlea because it maintains hair cell gene loci in a more transcriptionally accessible state.
    1. Computational and Systems Biology
    2. Neuroscience

    FoxP2 isoforms delineate spatiotemporal transcriptional networks for vocal learning in the zebra finch

    Zachary Daniel Burkett et al.
    Basal ganglia gene coexpression patterns shift across the sensorimotor critical period for vocal learning.