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    1. Neuroscience

    Unsupervised discovery of temporal sequences in high-dimensional datasets, with applications to neuroscience

    Emily L Mackevicius et al.
    Building on simple unsupervised matrix factorization techniques, the seqNMF algorithm successfully recovers neural sequences in a wide range of simulated and real datasets.
    1. Neuroscience

    Multiple mechanisms link prestimulus neural oscillations to sensory responses

    Luca Iemi et al.
    Neural oscillations prior to a stimulus modulate the strength of early and late responses in opposite directions via distinct mechanisms.
    1. Neuroscience

    Optogenetically induced low-frequency correlations impair perception

    Anirvan Nandy et al.
    Low-frequency correlations among neurons in monkey visual area V4 impair the animal's ability to perform an attention-demanding task, suggesting a causal role of these fluctuations in perception.
    1. Neuroscience

    Surface color and predictability determine contextual modulation of V1 firing and gamma oscillations

    Alina Peter et al.
    Colored surfaces induce strong gamma-synchronization yet sparse firing in V1 when receptive field inputs are predicted from the surrounding spatial context.
    1. Physics of Living Systems

    Negative reciprocity, not ordered assembly, underlies the interaction of Sox2 and Oct4 on DNA

    John W Biddle et al.
    Rigorous reanalysis of single-molecule data yields evidence for energy expenditure in the interaction of transcription factors on DNA.
    1. Neuroscience

    Decoupling sensory from decisional choice biases in perceptual decision making

    Daniel Linares et al.
    Perceptual decision making, even in simple scenarios, is affected by sensory and decisional choice biases.
    1. Neuroscience

    Noninvasive quantification of axon radii using diffusion MRI

    Jelle Veraart et al.
    Cell-specific architectural properties such as the axon diameter of the white matter of the human brain can be quantified accurately and non-invasively using diffusion magnetic resonance imaging.
    1. Neuroscience

    Functional clustering of dendritic activity during decision-making

    Aaron Kerlin et al.
    In motor cortex pyramidal neurons, diverse task-related signals are distributed throughout the dendritic arbor and compartmentalized by dendritic distance and branching.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Modeling the dynamics of Plasmodium falciparum gametocytes in humans during malaria infection

    Pengxing Cao et al.
    A mathematical model of blood-stage infection with Plasmodium falciparum malaria capturing the sexual stage of the parasite life-cycle is validated against human data, providing new insight into human-to-mosquito transmission.
    1. Computational and Systems Biology
    2. Neuroscience

    Multivariate stochastic volatility modeling of neural data

    Tung D Phan et al.
    Multivariate stochastic volatility models provide insights into understanding the dynamics and connectivity of neural signals during cognitive tasks.