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Microbiology and Infectious Disease
Nanoscale organization of rotavirus replication machineries
Yasel Garcés Suárez et al.
Super-resolution microscopy reveals, at nanometric-scale, the highly organized protein structure of viroplasms, the viral factories used by rotavirus to replicate its genome and assemble new viral particles.
Visual attention modulates the integration of goal-relevant evidence and not value
Pradyumna Sepulveda et al.
Visual attention modulates the integration of the evidence that is most useful for achieving a goal in both perceptual and value-based decisions.
FluoEM, virtual labeling of axons in three-dimensional electron microscopy data for long-range connectomics
Florian Drawitsch et al.
Methodology to annotate the multiple origins of axonal projections in dense electron microscopy data of mammalian nervous tissue without the need of chemical label conversion is reported.
Biochemistry and Chemical Biology
Structural Biology and Molecular Biophysics
Modulation of formin processivity by profilin and mechanical tension
Luyan Cao et al.
Profilin helps to maintain formin at the growing barbed end of an actin filament, while piconewton mechanical tension drastically enhances formin dissociation from the barbed end.
Computational and Systems Biology
Genetics and Genomics
Global donor and acceptor splicing site kinetics in human cells
Leonhard Wachutka et al.
Transient transcriptome sequencing and kinetic modeling suggest how the kinetics and yield of RNA splicing are encoded in the human genome.
A resource-rational theory of set size effects in human visual working memory
Ronald van den Berg, Wei Ji Ma
Set size effects in visual working memory are explained as a resource-rational trade-off between an error-based behavioral cost and a neural encoding cost.
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