In addition to causing DNA damage, R-loops cause genomic instability by interfering with DNA repair.

An unbiased RNAseq based strategy to identify targetable pathways and a streamlined lentiviral system provide a state of the art advance on direct fibroblast to neuron conversion.

A derived stress response trait may have contributed to the emergence of a globally dominant and promiscuous parasite.

Endothelial cells in the heart have transcriptional and epigenetic signatures of cardiomyocytes.

The elongation rate of RNA Polymerase II varies greatly between and along genes, as this enzyme accelerates from stable pausing to rapid elongation within genes, and is influenced by CG-content, exons and chromatin.

An ensemble of conserved G2-quadruplex structures in the untranslated regions of messenger RNAs from genes in the polyamine bioysynthesis pathway sense polyamine levels and regulate polyamine synthesis in cells.

Small RNAs of distantly related plant pathogens, such as fungi and oomycetes, hijack the plant RNA-induced silencing complex to favor host infection.

The transcriptomic profiles of the constituent monotherapies of synergistic drug pairs tend to be correlated and result in novel gene expression in the combinations.

PTBP2 ensures that adult protein variants are expressed only in mature neurons through regulation of alternative splicing during early neuronal development.

Live-cell nanometer-resolution RNA labeling method enables transcriptome-wide mapping of endogenous RNAs in nuclear, cytosol, ER, and mitochondrial subcompartments.