Nathan R Johnson, Luis F Larrondo ... Elena A Vidal
A critical assessment of published microRNA/microRNA-like provides clues on features and conservation of these hairpin RNAs in fungi in addition to a centralized loci annotation resource for the community.
Claudia Scheckel, Elodie Drapeau ... Robert B Darnell
Neuronal ELAV-like (nELAVL) proteins are associated with non-coding Y RNAs in stressed neurons and in the brains of Alzheimer's disease patients, suggesting a new means of regulatory protein sequestration and mRNA target regulation.
Mehdi Goudarzi, Kathryn Berg ... Alexander F Schier
Defining the biological functions of long non-coding RNAs, individually or as a class, and teasing apart the role of underlying genomic sequences remains the biggest challenge for this field.
Rebecca Feyh, Nadine B Waeber ... Florian Altegoer
The novel cryo-electron microscopy structure of a bacterial protein-only RNase P illustrates how a small protein oligomerizes into a dodecameric assembly to catalyze the 5’-end maturation of tRNAs.
Qinyu Hao, Minxue Liu ... Kannanganattu V Prasanth
A novel family of nucleolus-enriched ncRNAs forms allele-specific territories on the nucleolar organizing region (NOR)-containing acrocentric chromosomes.