Human gut bacteria alter their metabolism in response to each other's presence, which causes their community dynamics to deviate from predictions that are based on mono-culture data.
Sebastián Giunti, María Gabriela Blanco ... Diego Rayes
PTEN mutations disrupt inhibitory GABAergic signaling, causing neurodevelopmental defects that can be mitigated by β-hydroxybutyrate, which activates DAF-16/FOXO and may offer a therapeutic approach for excitation/inhibition imbalances.
Genetic analyses in budding yeast coupled with biochemical assays have revealed an unexpected role for the Smc5/6 complex in cellular pathways responsible for the prevention of RNA formation in genomic DNA.
Affinity capture of polyribosomes followed by RNAseq(ACAPSeq) is a technique that harnesses massively parallel sequencing to identify protein-protein interactions from any source from which polyribosomes can be purified.
Individuals with reversed congenital cataracts perceived visual events as occurring earlier than auditory and tactile events revealing that cross-modal temporal biases depend on sensory experience during an early sensitive period.
Sofia Battaglia, Michael Lidschreiber ... Patrick Cramer
In vivo and in vitro elongation factor-RNA interaction data provide a missing link in understanding how processive elongation complexes are formed on active genes and disassembled at the end of genes.
Gabriela Santos-Rodriguez, Irina Voineagu, Robert J Weatheritt
An analysis of the genomic features that distinguish conserved from species-specific circular RNAs reveals that the expansion of the downstream intron by insertion of retrotransposons stabilizes circular RNAs' production across 30+ millions years of evolution.
Attractive and repulsive history biases in visual perception occur simultaneously, yet over dissociable timescales, and are explained by efficient encoding and Bayesian decoding of visual information in a stable environment.
Fitting a simple model of COVID-19 transmission to crowdsourced case report data allowed the estimation of mean cluster size and transmission rates in Canadian schools, as well as determining which interventions are most likely to limit transmission.
