5,216 results found
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study

    Amanda M Hughes, Eleanor Sanderson ... Neil M Davies
    It is unclear how much a child's BMI at age 8 affects their depressive and ADHD symptoms after family-level factors are accounted for, but a substantial impact on anxiety symptoms is unlikely.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study

    Charles N Agoti, Lynette Isabella Ochola-Oyier ... George Githinji
    Genomic analysis of initial SARS-CoV-2 waves in Kenya revealed Mombasa City as a key gateway for variants entering Coastal Kenya with onward inter-county transmission highlighting significance of surveillance in major cities for early warning of lineages entering local populations.
    1. Evolutionary Biology

    The age of Homo naledi and associated sediments in the Rising Star Cave, South Africa

    Paul HGM Dirks, Eric M Roberts ... Lee R Berger
    Independent dating techniques have established that the H. naledi fossils are between 236 and 335 thousand years old, indicating that small-brained hominins with relatively primitive body shapes co-existed with our early ancestors in Africa.
    1. Cell Biology
    2. Immunology and Inflammation

    ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin

    Cristina Cacho-Navas, Carmen López-Pujante ... Jaime Millán
    ICAM-1 engagement controls hepatic cell polarity, but this receptor can also signal without prior leukocyte interaction, thanks to its confinement into apical, microvilli-enriched, bile-canalicular domains and its actin connector EBP50.
    1. Cell Biology
    2. Neuroscience

    MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

    Andrea Toledo, Mathieu Letellier ... Olivier Thoumine
    MDGAs are highly diffusive molecules that alter both neuroligin-1 and AMPA receptor dynamics and function, thereby significantly delaying the differentiation of excitatory post-synapses.
    1. Ecology

    Algal-fungal symbiosis leads to photosynthetic mycelium

    Zhi-Yan Du, Krzysztof Zienkiewicz ... Gregory M Bonito
    The capacity for symbiosis between photosynthetic microalgae and early diverging lineages fungi was demonstrated with microscopy and stable isotope exchange of carbon and nitrogen.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

    Amrita A Iyer, Ishwar Hosamani ... Andrew K Groves
    Cells of the mammalian cochlea can be reprogrammed to produce mechanosensory hair cells, but epigenetic changes in the cochlea make this process less efficient with age.
    1. Developmental Biology
    2. Neuroscience

    Direct glia-to-neuron transdifferentiation gives rise to a pair of male-specific neurons that ensure nimble male mating

    Laura Molina-García, Carla Lloret-Fernández ... Richard J Poole
    A novel developmental mechanism generates a previously undescribed pair of sex-specific proprioceptive neurons required for male-specific behaviour.
    1. Cell Biology
    2. Developmental Biology

    Visualizing the metazoan proliferation-quiescence decision in vivo

    Rebecca C Adikes, Abraham Q Kohrman ... David Q Matus
    During organismal development, CDK activity at mitotic exit is predictive of future cell behavior, indicating whether a cell will divide again or enter a quiescent state.
    1. Biochemistry and Chemical Biology

    Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

    Sara M Nowinski, Ashley Solmonson ... Jared Rutter
    Mitochondrial fatty acid synthesis is best known for producing lipoic acid, however, longer acyl chain products regulate mitochondrial electron transport chain assembly, oxidative TCA cycle metabolism, and skeletal myoblast differentiation.

Refine your results by:

Type
Research categories