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    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

    Huan Yan, Guocai Zhong ... Wenhui Li
    Biochemical and genetic tests have revealed that a liver protein called NTCP is a functional receptor for hepatitis B and D viruses, which should lead to an improved understanding of the infections caused by these viruses and assist the development of new intervention strategies.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

    Jerome S Menet, Joseph Rodriguez ... Michael Rosbash
    Genome-wide measurements on mouse liver cells show that transcription, and a particular key transcription factor, have a smaller than expected influence on the mouse circadian system.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A novel role for lipid droplets in the organismal antibacterial response

    Preetha Anand, Silvia Cermelli ... Steven P Gross
    Histones bound to lipid droplets inside cells offer protection against bacteria in flies, and possibly mice, thus suggesting a possible new innate immunity pathway.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex

    Tsutomu Aoki, Ali Sarkeshik ... Paul Schedl
    A chromatin boundary factor that is only active during early embryo development has been discovered in Drosophila.
    1. Biochemistry and Chemical Biology

    RecA filament sliding on DNA facilitates homology search

    Kaushik Ragunathan, Cheng Liu, Taekjip Ha
    A DNA–protein complex can find target sequences of bases in another DNA molecule by sliding along it.
    1. Neuroscience

    The activity-dependent histone variant H2BE modulates the life span of olfactory neurons

    Stephen W Santoro, Catherine Dulac
    A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Global divergence in critical income for adult and childhood survival: analyses of mortality using Michaelis–Menten

    Ryan J Hum, Prabhat Jha ... Yu-Ling Cheng
    A mathematical model based on enzyme kinetics shows how the relationships between life expectancy, survival rates for children and adults, and national income change over time.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

    Jiajie Diao, Patricia Grob ... Axel T Brunger
    A combination of advanced optical imaging and cryogenic electron microscopy has been used to explore membrane fusion in a synthetic system and provide new insights into neurotransmitter release.