Optogenetic activation of Rho GTPases provides spatiotemporal control over endothelial cell shape and enables control over endothelial barrier function by manipulating the cell-cell overlap with blue light.

Detecting neural oscillations in time and frequency domains enables the detailed study of spatiotemporal dynamics of oscillations throughout the brain and the investigation of biomarkers that index functional brain areas.

Histone deacetylase 1 (Hdac1) plays a crucial role in maintaining differential histone acetylation states of enhancers in various germ layers and regulates the transcriptional program both temporally and spatially.

The adhesion-GPCR BAI1 shapes dendritic arbors in the hippocampus by associating with Bcr late in development and stimulating its RhoA-GEF activity, resulting in dendritic growth arrest.

Visual, parietal, and frontal motor cortices play distinct and necessary roles in mapping sensory features to future motor action.

Single-cell RNA sequencing of Drosophila hemocytes in blood distinguishes various states within known blood cell types and implicates a novel role for fibroblast growth factor receptor signaling in inter-hemocyte crosstalk.

Transferred mitochondria do not always regulate cell behavior by simply restoring mitochondrial function, but rather, transferred mitochondria are dysfunctional, initiating downstream signaling and proliferation in response to reactive oxygen species.

An unprecedented large-scale screen in mice for morphogenetic regulators of tissue development provides major new insights into the roles of Rho GTPases in diverse array of skin developmental processes.

Muscle synergies are able to identify muscular adaptation that results from feelings of joint instability, whereas tibiofemoral kinematics are sensitive for detecting acute instability events during functional activities.

Diverse and widespread novel alternative pre-mRNA splicing isoforms as well as cycling alternative splicing events that undergo time-of-day dependent changes are identified in isolated Drosophila neuron groups.