419 results found
    1. Neuroscience

    A multicellular rosette-mediated collective dendrite extension

    Li Fan et al.
    Migrating skin carries the amphid rosette vertex anteriorly to extrude and position dendrites.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Predicted glycosyltransferases promote development and prevent spurious cell clumping in the choanoflagellate S. rosetta

    Laura A Wetzel et al.
    A genetic screen reveals that two predicted glycosyltransferases promote rosette development and prevent cell clumping in one of the closest living relatives of animals, the choanoflagellate S. rosetta.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Engineering induction of singular neural rosette emergence within hPSC-derived tissues

    Gavin T Knight et al.
    A bioengineering approach identifies tissue morphology as an effective variable for controlling the inception of neural organoid morphogenesis via induction of a biomimetic, singular neural rosette tissue cytoarchitecture.
    1. Developmental Biology
    2. Genetics and Genomics

    The rosetteless gene controls development in the choanoflagellate S. rosetta

    Tera C Levin et al.
    The establishment of forward genetics in S. rosetta reveals the first gene known to be required for choanoflagellate multicellular development.
    1. Structural Biology and Molecular Biophysics
    2. Computational and Systems Biology

    Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta

    Ray Yu-Ruei Wang et al.
    Extensive benchmarking reveals that errors made when manually building models into near-atomic-resolution cryoEM density may automatically be corrected using an improved Rosetta-based structure refinement method.
    1. Physics of Living Systems

    Aerotaxis in the closest relatives of animals

    Julius B Kirkegaard et al.
    The colony-forming choanoflagellate Salpingoeca rosetta is capable of moving towards oxygen using logarithmic sensing of oxygen concentrations and a navigation strategy that involves random movements.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Cell Division: Turning cell cycle entry on its head

    Cosetta Bertoli, Robertus Antonius Maria de Bruin
    Insight
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    1. Cell Biology
    2. Microbiology and Infectious Disease

    Three F-actin assembly centers regulate organelle inheritance, cell-cell communication and motility in Toxoplasma gondii

    Nicolò Tosetti et al.
    Toxoplasma gondii formins have several non-overlapping roles including generating an apico-basal flux of F-actin that is controlled by phosphorylation and methylation and is essential for motility.
    1. Neuroscience

    Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury

    Josette J Wlaschin et al.
    The DLK response pathway in neurons initiates the cascade of events leading to neuropathic pain after injury.
    1. Developmental Biology
    2. Genetics and Genomics

    Multicellularity: Forward genetics for back-in-time questions

    Alex de Mendoza, Iñaki Ruiz-Trillo
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