Aline Jelenkovic, Yoon-Mi Hur ... Karri Silventoinen
Genetic variance of adult human height shows a generally increasing trend across the birth-year cohorts but heritability estimates do not present any clear pattern of secular changes over a century.
Numerous related sample characteristics affect polygenic score performance, and incorporation of interaction effects increases both model and polygenic score performance.
Eileen P Hamilton, Aurélie Kapusta ... Robert S Coyne
The model organism Tetrahymena thermopile carries two nuclei with distinct genomes: an unrearranged germline genome with five chromosomes, and a somatic genome reduced in size by a third and with 181 chromosomes.
Romeo Papazyan, Ekaterina Voronina ... Sean D Taverna
A previously unappreciated histone methylation pathway helps limit DNA double-strand break formation and recombination in heterochromatin during meiosis.
M Fernanda López-Gutiérrez, Zeus Gracia-Tabuenca ... Sarael Alcauter
Brain functional connectivity shows a neurobiological predisposition to social bonding, and network-wide changes occur as a result of cohabitation in the prairie vole.
Adrian L Sanborn, Benjamin T Yeh ... Roger D Kornberg
Transcriptional activation domains achieve rapid, dynamic, specific interaction with Mediator through binding of an unstructured peptide to multiple hydrophobic surfaces without particular amino acid side chain interactions.