3,376 results found
    1. Genes and Chromosomes

    Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae

    Nicola Manfrini et al
    The conversion of the ends of a double-strand break from double-stranded to single-stranded DNA, which is necessary to initiate homologous recombination, is responsible for loss of transcription and RNA polymerase occupancy around the double-strand break in Saccharomyces cerevisiae.
    Research Article Updated
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    1. Genes and Chromosomes

    The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae

    Evan P Hass, David C Zappulla
    In yeast, the secondary pathway for recruiting telomerase to chromosome ends requires a component of telomeric transcriptionally silent chromatin.
    Research Article Updated
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    1. Ecology
    2. Genomics and Evolutionary Biology

    The Natural History of Model Organisms: The fascinating and secret wild life of the budding yeast S. cerevisiae

    Gianni Liti
    The yeast Saccharomyces cerevisiae has informed our understanding of molecular biology and genetics for decades, and learning more about its natural history could fuel a new era of functional and evolutionary studies of this classic model organism.
    Feature Article
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    1. Cell Biology
    2. Genes and Chromosomes

    Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres

    Jan Wisniewski et al
    Internally tagged, functional Cse4/CENP-A/CenH3 histone variant is exclusively centromeric and stable through the budding yeast cell cycle after replacement in S phase.
    Research Article Updated
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    1. Developmental Biology and Stem Cells
    2. Genomics and Evolutionary Biology

    The rosetteless gene controls development in the choanoflagellate S. rosetta

    Tera C Levin et al
    The establishment of forward genetics in S. rosetta reveals the first gene known to be required for choanoflagellate multicellular development.
    Research Article Updated
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    1. Developmental Biology and Stem Cells
    2. Genes and Chromosomes

    The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation

    Shauna L Houlihan, Yuanyi Feng
    Differentiation-specific maintenance of genome integrity during S-phase is essential for establishing both the structure and function of the cerebral cortex.
    Research Article
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    1. Neuroscience

    Correction: Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster

    César S Mendes et al
    Correction
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    1. Neuroscience

    Correction: Acute inhibition of neurosteroid estrogen synthesis suppresses status epilepticus in an animal model

    Satoru M Sato, Catherine S Woolley
    Correction
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    1. Developmental Biology and Stem Cells
    2. Neuroscience

    Antibody Engineering: Falling apart

    Jonathan S Marvin, Loren L Looger
    Insight
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    1. Biochemistry
    2. Biophysics and Structural Biology

    Antimicrobials: A lysin to kill

    Anthony O Gaca, Michael S Gilmore
    Insight
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