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Cell Biology: New twists in the unfolded protein response
Benedict C S Cross, David Ron
Research: Titles and abstracts of scientific reports ignore variation among species
Barbara R Migeon
Ignoring the probability of species variation when reporting observations about biological processes leads to misinterpretation of the experimental data.
The Natural History of Model Organisms: From molecular manipulation of domesticated
to survival in nature
Severin Sasso et al.
Dubbed the 'green yeast', the model alga
has profoundly advanced many areas of biology, but much remains to be learnt about its life in the wild.
Microbiology and Infectious Disease
Bacteria: Exploring new horizons
Vineetha M Zacharia, Matthew F Traxler
bacteria employ a newly-discovered cell type, the "explorer" cell, to rapidly colonize new areas in the face of competition.
Computational and Systems Biology
Genetic Novelty: How new genes are born
Urminder Singh, Eve Syrkin Wurtele
Analysis of yeast, fly and human genomes suggests that sequence divergence is not the main source of orphan genes.
The Natural History of Model Organisms:
outside the Petri dish
Lise Frézal, Marie-Anne Félix
To leverage the tools, resources and knowledge that exist for
so that we can study ecology, evolution and other aspects of biology, we need to understand the natural history of this important model organism.
Structural Biology and Molecular Biophysics
PIE-scope, integrated cryo-correlative light and FIB/SEM microscopy
Sergey Gorelick et al.
The PIE-scope resolves the limitations in correlative cryo-focused ion beam milling by adding robustness and ease of use to the workflow.
Genetics and Genomics
The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay
Karole N D'Orazio et al.
Cue2 is an endonuclease that cleaves mRNA in the A site of the lagging ribosome upon ribosome collision events.
Genetics and Genomics
The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs
Axelle Marchant et al.
Regulatory evolution allows paralogs to escape from strucural pleiotropy.
Biochemistry and Chemical Biology
An explanation for origin unwinding in eukaryotes
Lance D Langston, Michael E O'Donnell
CMG helicase translocates with force while encircling duplex DNA, enabling two opposing CMG complexes at an origin to melt the duplex and switch to encircling separate single strands.
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