When making two decisions about one object, two streams of information can be acquired in parallel but must be incorporated into the two decisions serially, consistent with a central bottleneck.
Our latest Special Issue brings together research covering many different aspects of the impact of the COVID-19 pandemic on cancer outcomes across the globe.
Anne Löffler, Ariel Zylberberg ... Daniel M Wolpert
Deciding which of two perceptual decisions is more difficult involves sequential sampling processes that terminate when the difference in accumulated evidence for each decision exceeds a threshold.
Morphological profiling of untreated HCT116 cells using Cell Painting reveals a signature of bortezomib resistance, providing a proof-of-concept for the unbiased analysis of drug resistance.
Clare M Smith, Richard E Baker ... Christopher M Sassetti
A novel dual genome approach that combines genetically diverse mice and a library of bacterial mutants to define the genome-wide host pathogen interactions that drive distinct outcomes to tuberculosis.
Comparing the white-footed deermouse with mice and rats in an inflammation model reveals a means for the observed infection tolerance in this key animal reservoir for several human diseases.
Systems analysis of antibody repertoires reveals that strong humoral responses lead to extensive B-cell overlap across multiple lymphoid organs, indicating physiological axes of B-cell migration and a direct correlation with antigen specificity.
