3,863 results found
    1. Evolutionary Biology
    2. Genetics and Genomics

    High social status males experience accelerated epigenetic aging in wild baboons

    Jordan A Anderson, Rachel A Johnston ... Jenny Tung
    Among the factors that predict fitness in wild baboons, dominance rank in males, but not in females, is the best predictor of epigenetic aging.
    1. Microbiology and Infectious Disease

    Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori

    Jennifer A Taylor, Benjamin P Bratton ... Nina R Salama
    The helical bacterium Helicobacter pylori patterns cell wall synthesis using two distinct cytoskeletal proteins, CcmA and MreB, to achieve its characteristic shape.
    1. Microbiology and Infectious Disease

    Multi-omics investigation of Clostridioides difficile-colonized patients reveals pathogen and commensal correlates of C. difficile pathogenesis

    Skye RS Fishbein, John I Robinson ... Gautam Dantas
    Integration of clinical patient data, pathogen information and a multi-omic analysis of the gut microbiome reveals key determinants of disease in C. difficile-colonized patients.
    1. Neuroscience

    The rapid developmental rise of somatic inhibition disengages hippocampal dynamics from self-motion

    Robin F Dard, Erwan Leprince ... Michel A Picardo
    The first postnatal week ends with the development of perisomatic innervation and with an abrupt switch in the representation of self-motion in the region CA1 of the mouse hippocampus.
    1. Developmental Biology
    2. Plant Biology

    Coordination of tissue cell polarity by auxin transport and signaling

    Carla Verna, Sree Janani Ravichandran ... Enrico Scarpella
    GNOM controls both auxin transport and auxin signaling to coordinate tissue cell polarity during vein patterning in plants.
    1. Evolutionary Biology

    Phylogenomic analyses of echinoid diversification prompt a re-evaluation of their fossil record

    Nicolás Mongiardino Koch, Jeffrey R Thompson ... Greg W Rouse
    Phylogenomics of sea urchins clarifies their origins and diversification history, reveals surprising discrepancies with their rich fossil record, and serves as basis to explore the sensitivity of time calibration analysis.
    1. Cell Biology
    2. Plant Biology

    The Arabidopsis SAC9 enzyme is enriched in a cortical population of early endosomes and restricts PI(4,5)P2 at the plasma membrane

    Alexis Lebecq, Mehdi Doumane ... Marie-Cécile Caillaud
    SAC9 prevents the accumulation of PI(4,5)P2 in intracellular compartments, thereby contributing to clathrin-mediated endocytosis at the plasma membrane and regulating the cortical localization of its protein partner SH3P2.
    1. Evolutionary Biology

    Phylogenomics of white-eyes, a ‘great speciator’, reveals Indonesian archipelago as the center of lineage diversity

    Chyi Yin Gwee, Kritika M Garg ... Frank E Rheindt
    Contrary to the high absolute number of white-eyes in other parts of the world, the Indonesian archipelago is the center of phylogenetic diversity of this great speciator.
    1. Evolutionary Biology

    Geological and taphonomic context for the new hominin species Homo naledi from the Dinaledi Chamber, South Africa

    Paul HGM Dirks, Lee R Berger ... Steven Tucker
    A new hominin species found in a South African cave is part of one of the most unusual hominin fossil assemblages on record.
    1. Cell Biology

    Exploring the role of macromolecular crowding and TNFR1 in cell volume control

    Parijat Biswas, Priyanka Roy ... Deepak Kumar Sinha
    Cells adapt to extracellular hypertonicities using regulatory volume increase (RVI), and TNFR1-mediated NFkB activation is indispensable for RVI, but the increased cytoplasmic macromolecular crowding can inhibit TNFR1 signaling and prevent RVI at severe hypertonicities.

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