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Bazedoxifene's SERD activities enable it to resist the impact of activating ESR1 mutations in breast cancer.

Auxin is produced in the endosperm after fertilization and drives the development of the seed coat in Arabidopsis.

Models of plant behaviour show that flowering early in a warming world is an adaptive strategy to insulate progeny seed behaviour from the affects of climate change.

The same membrane trafficking cargo can change pathways mediated by different members of ARF-GEF family of vesicle formation regulators.

Given sufficient population adherence, mass drug administration for falciparum malaria can provide group level benefits, also known as ‘herd effects’.

Indoxyl sulfate, a key uremic toxin in chronic kidney disease (CKD), induces trained immunity in monocytes via crosstalk between aryl hydrocarbon receptor (AhR)-dependent epigenetic reprogramming by enhancement of the arachidonic acid pathway and AhR-independent metabolic rewiring.

Seed-specific and cold-induced DNA methylation is deposited in the seed progeny to form a transient and transgenerational memory of past environmental conditions to optimize seed germination timing.

Arabidopsis shows extensive genetic diversity in germination time distributions, which can be explained by the underlying ABA/GA network functioning as a noisy bistable switch.

A robust fluorescence microscopy-based data acquisition and analysis framework affords the precise measurement of cell surface receptor affinities toward their cognate ligands and their densities in live cells/tissues.

Fruit consumption of Jeholornis was evidenced and indicates seed dispersal was present from early in avian radiation.