180 results found
    1. Cell Biology

    Novel Mechanism for Tubular Injury in Nephropathic Cystinosis

    Swastika Sur, Maggie Kerwin ... Minnie M Sarwal
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Neuroscience

    Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory

    Naoki Yamawaki, Hande Login ... Asami Tanimura
    Unveiling the circuit organization and functional roles of endopiriform neurons projecting to the ventral CA1.
    1. Neuroscience

    Mixed representations of choice direction and outcome by GABA/glutamate cotransmitting neurons in the entopeduncular nucleus

    Julianna Locantore, Yijun Liu ... Michael Wallace
    Basal ganglia output from the entopeduncular nucleus to the lateral habenula is not required for performance in a probabilistic switching task that requires flexible action/outcome decision making.
    1. Neuroscience

    A septo-hypothalamic-medullary circuit directs stress-induced analgesia

    Devanshi Piyush Shah, Pallavi Raj Sharma ... Arnab Barik
    Acute stress and anxiety can suppress pain, here we reveal a multi-nodal circuit in the brain that connects the two.
    1. Neuroscience

    Valence and salience encoding in the central amygdala

    Mi-Seon Kong, Ethan Ancell ... Larry S Zweifel
    Central amygdala neurons encode the valence and salience of unconditioned stimuli.
    1. Computational and Systems Biology

    Statistical analysis supports pervasive RNA subcellular localization and alternative 3' UTR regulation

    Rob Bierman, Jui M Dave ... Julia Salzman
    Analysis of genome-wide spatial transcriptomics data reveals cell-type specific subcellular RNA localization, and a subset of genes show significantly high correlation between spatial patterning and 3' UTR length.
    1. Neuroscience

    Midbrain encodes sound detection behavior without auditory cortex

    Tai-Ying Lee, Yves Weissenberger ... Johannes C Dahmen
    Behavior is a major determinant of the activity of auditory midbrain neurons and can shape their responses independently of input from the auditory cortex.
    1. Neuroscience

    The cation channel mechanisms of subthreshold inward depolarizing currents in the mice VTA dopaminergic neurons and their roles in the chronic-stress-induced depression-like behavior

    Jing Wang, Min Su ... Hailin Zhang
    NALCN and TRPC6 drive the subthreshold depolarization of VTA DA neurons and down regulation of TRPC6 contributes to reduced VTA DA neuron firing and chronic stress-induced depression-like behavior of mice.
    1. Developmental Biology

    FGF8-mediated gene regulation affects regional identity in human cerebral organoids

    Michele Bertacchi, Gwendoline Maharaux ... Michèle Studer
    A novel 2D-to-3D human brain organoid protocol reveals the pivotal role of FGF8 signaling in driving regional patterning and cellular diversity, while also modulating genes crucial for both normal and pathological neural development.
    1. Microbiology and Infectious Disease

    Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages

    Shuai Ma, Bin Yang ... Lingyan Jiang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete

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