10,945 results found
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling

    Lukasz Kedzierski et al.
    The intracellular SOCS5 protein has a unique and key role in restraining influenza A infection by regulating epidermal growth factor receptor signaling in airway epithelial cells.
    1. Epidemiology and Global Health

    A century of trends in adult human height

    NCD Risk Factor Collaboration (NCD-RisC)
    Height in early adulthood is an indicator that integrates across different dimensions of sustainable human development with links to health and longevity, nutrition, education and economic productivity.
    1. Neuroscience

    Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice

    Samantha Washburn et al.
    Acute knock down of Sgce that is mutated in Myoclonus Dystonia (DYT11), in the cerebellum of mice, leads to dystonia and myoclonus-like motor signs that like patients improve with alcohol.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Many lncRNAs, 5’UTRs, and pseudogenes are translated and some are likely to express functional proteins

    Zhe Ji et al.
    Thousands of "noncoding" RNAs, 5' "untranslated" regions, and pseudogenes in humans are actually translated, and some of these are likely to express functional proteins.
    1. Epidemiology and Global Health

    Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

    NCD Risk Factor Collaboration (NCD-RisC)
    Changes in the prevalence of underweight, total obesity, and severe obesity are largely driven by shifts in the distribution of body mass index.
    1. Ecology
    2. Evolutionary Biology

    Comparative genomics explains the evolutionary success of reef-forming corals

    Debashish Bhattacharya et al.
    The analysis of 20 coral genomic datasets provides unprecedented insights into what makes reef-building corals unique, including the evolution of novel gene families involved in biomineralization, signaling and stress responses that have led to their evolutionary success throughout the Phanerozoic Eon.
    1. Cell Biology

    Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity

    Ana Paula Arruda et al.
    Store operated calcium entry is defective in hepatocytes of obese mice, and restoring this process is sufficient to improve glucose metabolism.
  1. Research Culture: A survey of early-career researchers in Australia

    Katherine Christian et al.
    Job insecurity is putting stress on early-career researchers in Australia, compromising their career development and potentially reducing the quality of research.
    1. Neuroscience

    Organization and function of Drosophila odorant binding proteins

    Nikki K Larter et al.
    A genetic analysis reveals that some olfactory sensilla of Drosophila do not require an abundant odorant binding protein and that one such protein may act in gain control.
    1. Neuroscience

    Output variability across animals and levels in a motor system

    Angela Wenning et al.
    Population output variability in a motor control system varies across levels (CPG, motor neurons, muscles) and can be ascribed to life history differences among animals and in some cases to differences between bilaterally homologous elements.

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