Adaptation of domesticated maize and its wild relative teosinte has been facilitated by the geographically widespread exchange of beneficial alleles between them.
SERBP1 is associate with protein complexes regulating splicing, cell division, and ribosomal biogenesis that likely depend on G quadruplex (G4) binding and polyADP-ribosylation (PARylation) for their assembly and function.
The light-modulated protein kinase CDK5 is important for phase shifts of the circadian clock, impacting phase delays through calcium influx and signaling pathways, crucial for adapting to jet lag.
Interleukin-1 activates RhoA/ROCK signaling, which drives the enrichment of actin bundles at the cell-cell junctions, preventing SARS-CoV-2 spreading via syncytia formation.
In P3 editing, molecular interactions are sensed and converted directly into genome editing events, which may be useful for biological recording and synthetic molecular circuits deployed in living cells.
