60 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The translational landscape of the splicing factor SRSF1 and its role in mitosis

    Magdalena M Maslon et al.
    Identifying the translational targets of the shuttling protein, SRSF1, reveals that it is needed for normal cell division, and suggests that it couples pre-mRNA splicing and translation.
    1. Chromosomes and Gene Expression
    2. Stem Cells and Regenerative Medicine

    SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program

    Madara Ratnadiwakara et al.
    RNA-binding protein SRSF3 mediates critical changes in RNA processing of pluripotency genes, which reveals functional consequences of regulated RNA processing during stem cell self-renewal and early development.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation

    Emilie Ma et al.
    The association of Rad52 with Rad51, while not critical for Rad51 filament formation, is crucial to protect Rad51 filaments from Srs2 translocase activity through the association of Rad52 with complete Rad51 filaments.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loops

    Jie Liu et al.
    The Srs2 helicase functions in Synthesis-Dependent Strand Annealing to avoid crossover formation during homologous recombination by disrupting D-loops that are extended by DNA polymerase delta in an ATP-dependent and direction-specific manner.
    1. Chromosomes and Gene Expression

    The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast

    Sanjeeta Tamang et al.
    Unloading the polymerase sliding clamp PCNA from DNA by Elg1 promotes recombination at the RTS1 replication fork barrier by limiting Fbh1 and Srs2 activity.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    SON and SRRM2 are essential for nuclear speckle formation

    İbrahim Avşar Ilik et al.
    Re-characterization of the targets of a commonly used nuclear speckle marker unexpectedly leads to the discovery of the elusive core of the nuclear speckles.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs

    Ian A Roundtree et al.
    YTHDC1 facilitates selective clearance of N6-methyladenosine methylated mRNAs from the nucleus to the cytoplasm through binding by nuclear 'reader' proteins and incorporation into the canonical mRNA export pathway.
    1. Chromosomes and Gene Expression

    Factors affecting template switch recombination associated with restarted DNA replication

    Manisha Jalan et al.
    Genomic deletions and gene conversions, caused by template switching associated with restarted DNA replication, are detected downstream of a collapsed replication fork and are suppressed by several conserved DNA helicases.
    1. Cell Biology
    2. Immunology and Inflammation

    IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs

    Hao Zhou et al.
    The stimulation of lipopolysaccharides induced nuclear localization of IRAK2 to facilitate nuclear export of a specific subset of inflammation-related messenger RNAs for translation in murine macrophages.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq

    Jason G Dumelie, Samie R Jaffrey
    Genome-wide profiling of R-loops at near single-nucleotide resolution reveals distinct R-loop boundaries depending on the presence and location of the first exon-intron junction.

Refine your results by:

Type
Research categories