The structure of the VemP-stalled ribosome reveals a helix-double turn-helix conformation of the nascent chain within the ribosomal tunnel, illustrating how secondary structure formation directly at the peptidyltransferase center of the ribosome can induce translational arrest.
A moth can detect plant volatiles using an odorant receptor expressing in its ovipositor, and this odorant receptor has a much higher expression level in the ovipositor than antennae.
The fidelity of 3D visual object representations, choice-related activity, and experience-dependent sensorimotor associations are functionally linked in the caudal intraparietal area.
Hippocampal neurons undergo bi-stable behavior as neurites emerge, and the dominance of either state is determined by environmental mechanical properties and paxillin-associated cellular endocytic activities.
CD40 signaling is necessary to generate the immediate precursors of GC B cells, transition to the BCL6hi follicular state is promoted by a regional and transient diminution of T cell help.
A protein within the nuclear membrane, MAN1, controls the expression of the circadian clock gene, BMAL1, in an example of cross-talk between two major gene regulatory pathways.
The determination that a decision-maker integrated evidence to form perceptual decisions is shown to be much more difficult than previously appreciated.
The important role of serine biosynthesis in Müller cells may explain why the macula is so much more prone to developing disease than the rest of the retina.
