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    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Transcription termination and antitermination of bacterial CRISPR arrays

    Anne M Stringer, Gabriele Baniulyte ... Joseph T Wade
    Many bacteria use the Nus factor antitermination complex to prevent premature Rho-dependent transcription termination of their CRISPR arrays.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Fitness benefits in fluoroquinolone-resistant Salmonella Typhi in the absence of antimicrobial pressure

    Stephen Baker, Pham Thanh Duy ... Maciej F Boni
    The major evolutionary routes to drug resistance in Salmonella Typhi are associated with fitness benefits, not fitness costs, implying that prudent antimicrobial use will have no effect as a public health intervention in controlling typhoid fever.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    A novel fold for acyltransferase-3 (AT3) proteins provides a framework for transmembrane acyl-group transfer

    Kahlan E Newman, Sarah N Tindall ... Marjan W Van Der Woude
    The modelled structure of a membrane protein supports the hypothesis that it has a new fold with a channel that allows a chemical group to cross the membrane to decorate surface structures.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    CCL28 modulates neutrophil responses during infection with mucosal pathogens

    Gregory T Walker, Araceli Perez-Lopez ... Manuela Raffatellu
    Chemokine CCL28 plays a key role in shaping neutrophil responses during intestinal Salmonella infection and lung Acinetobacter infection.
    1. Microbiology and Infectious Disease

    Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages

    Shuai Ma, Bin Yang ... Lingyan Jiang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages

    Marisa S Egan, Emily A O’Rourke ... Sunny Shin
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

    Mehabaw G Derebe, Clare M Zlatkov ... Lora V Hooper
    Serum amyloid A proteins bind retinol with nanomolar affinity, and do so by forming oligomers that create a hydrophobic pocket that shields retinol from the aqueous environment.
    1. Microbiology and Infectious Disease

    Genetic code expansion enables visualization of Salmonella type three secretion system components and secreted effectors

    Moirangthem Kiran Singh, Parisa Zangoui ... Linda J Kenney
    Genetic code expansion (GCE) enables site-specific labeling and visualization of Salmonella secreted effectors, secretion system components and provides a viable alternative for labeling proteins that do not tolerate N- or C-terminal tags.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Length-dependent flagellar growth of Vibrio alginolyticus revealed by real time fluorescent imaging

    Meiting Chen, Ziyi Zhao ... Chien-Jung Lo
    The length-dependent growth rate of bacterial flagellar filament is determined by the flagellin loading speed, loading strength and its diffusion process.