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  1. Research Culture: Framework for advancing rigorous research

    Walter J Koroshetz et al.
    Establishing a community of 'rigor champions' and building a comprehensive educational platform to teach the principles of rigorous science will help to ensure that the outputs of scientific research remain reliable and robust.
  2. Philosophy of Biology: Health, ecology and the microbiome

    S Andrew Inkpen
    The interactions between communities of microbial species and their human hosts raise questions about the nature of health and disease.
  3. Meta-Research: How significant are the public dimensions of faculty work in review, promotion and tenure documents?

    Juan P Alperin et al.
    An analysis of review, promotion and tenure documents from 129 US and Canadian universities suggests institutions could better fulfill their public missions by changing how they incentivize the public dimensions of faculty work.
  4. Philosophy of Biology: Philosophical bias is the one bias that science cannot avoid

    Fredrik Andersen et al.
    Scientists should be aware of the non-empirical assumptions that influence all kinds of research.
    1. Ecology

    Biodiversity: Making wildlife welcome in urban areas

    Travis Gallo, Mason Fidino
    Careful design of the green spaces in cities will benefit both wild animals and humans.
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    1. Neuroscience

    Navigation: Shedding light on stellate cells

    Andrew S Alexander, Michael E Hasselmo
    The relationship between grid cells and two types of neurons found in the medial entorhinal cortex has been clarified.
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    1. Neuroscience

    Amyotrophic Lateral Sclerosis: Marking the differences in motoneurons

    Simon A Sharples, Patrick J Whelan
    A subgroup of the neurons that control muscles becomes less excitable shortly before the symptoms of ALS develop.
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    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    Gastrulation: May the force be with you

    Shinuo Weng, John B Wallingford
    Understanding the coordination of the forces generated in embryos by two processes, convergent extension and convergent thickening, is key to understanding how a hollow sphere of cells develops into an elongated embryo.
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    1. Neuroscience

    Computational Psychiatry: Exploring atypical timescales in the brain

    Leonardo L Gollo
    Identifying activity imbalances in specific brain regions may help to diagnose and treat psychiatric disorders.
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    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.