2,303 results found
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A unifying mechanism for the biogenesis of membrane proteins co-operatively integrated by the Sec and Tat pathways

    Fiona J Tooke et al.
    Bioinformatics and experimental approaches identify families of membrane proteins requiring the co-ordinated action of the Sec pathway and Tat pathways for their integration and define features of the polypeptides that mediate interaction with these pathways.
    1. Chromosomes and Gene Expression

    Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan

    Zheng Hu et al.
    Activation of the stress response pathway in young cells extends replicative lifespan, not by reducing global protein synthesis per se, but by Gcn4-mediated autophagy induction.
    1. Developmental Biology

    The Natural History of Model Organisms: An organismal perspective on C. intestinalis development, origins and diversification

    Matthew J Kourakis, William C Smith
    The life cycle and morphology of the sea squirt Ciona intestinalis shed light on vertebrate evolution.
    1. Neuroscience

    Connectomics: Think small

    Luis A Bezares-Calderón, Gáspár Jékely
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    1. Neuroscience

    Navigation: Shedding light on stellate cells

    Andrew S Alexander, Michael E Hasselmo
    The relationship between grid cells and two types of neurons found in the medial entorhinal cortex has been clarified.
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    1. Neuroscience

    Brain Evolution: Adaptations to extreme conditions

    Barbara S Beltz
    The brain architecture of shrimp living in deep-sea vents provides clues to how these organisms have adapted to extreme living.
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  1. Point of View: The future of graduate and postdoctoral training in the biosciences

    Peter Hitchcock et al.
    What can institutions and funding agencies do to address an array of issues facing the biomedical research community in the United States?
  2. Living Science: The importance of remembering

    Eve Marder
    Creativity in science requires the ability to recall information and data, and will suffer if we rely too much on technology to remember things for us.
    1. Cell Biology
    2. Human Biology and Medicine

    Carcinogenesis: Targeting the link between late pregnancy and breast cancer

    Balabhadrapatruni VSK Chakravarthi, Sooryanarayana Varambally
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