Elizabeth M Sefton, Mirialys Gallardo ... Gabrielle Kardon
HGF derived from fibroblasts is critical for complete muscularization of the mammalian diaphragm, and loss-of-function experiments reveal that partial muscularization of the diaphragm is not sufficient to cause congenital diaphragmatic hernias.
Ann Kathrin Heilig, Ryohei Nakamura ... Toru Kawanishi
A medaka mutant revealed that Wnt11 promotes formation of uniquely large protrusions from non-myogenic dorsal dermomyotome cells, which guide the epaxial myotome dorsally to achieve the coverage of the neural tube.
A neuroprotective role mediated by Strip1 maintains retinal ganglion cells during development, which ensures proper positioning of inner retinal neurons and preserves the laminar architecture of the inner retina.
Fernando Martín-Fernández, Ana Bermejo-Santos ... Marta Nieto
Transient expression of Nrp1 is required in postnatal stages for terminal arborization and innervation of secondary areas during the development of somatosensory callosal circuits.
Oscar Urtatiz, Amanda Haage ... Catherine D Van Raamsdonk
G alpha q/11 signaling can either promote or inhibit melanocyte growth through a reversible switch that is controlled by the microenvironment and that shapes the mutational diversity of melanoma subtypes.
Benoît Boulan, Charlotte Ravanello ... Jean-Christophe Deloulme
CRMP4 is a new actor in the guidance cue Semaphorin-3E pathway, crucially involved in the establishment of the fornix, a key axonal tract for memory and emotional control.
Adult neural stem cells differ in the types of neurons they generate according to their location and new territories and genes associated with dorsal and ventral neurogenic lineages in the adult mouse brain are revealed.