10 results found
    1. Microbiology and Infectious Disease

    In situ imaging of bacterial outer membrane projections and associated protein complexes using electron cryo-tomography

    Mohammed Kaplan et al.
    Electron cryo-tomography reveals that bacteria can form structurally-diverse outer membrane extensions with various protein complexes associated with them.
    1. Biochemistry and Chemical Biology

    Post-translational flavinylation is associated with diverse extracytosolic redox functionalities throughout bacterial life

    Raphaël Méheust et al.
    Bioinformatic and biochemical studies provide evidence that covalently bound flavins are common and participate in wide-ranging extracytosolic redox activities throughout bacterial life.
    1. Microbiology and Infectious Disease

    Specificity in glycosylation of multiple flagellins by the modular and cell cycle regulated glycosyltransferase FlmG

    Silvia Ardissone et al.
    Glycosylation of flagellins with pseudaminic acid in the bacterial cytoplasm governed by an unknown type of modular glycosyltransferase harboring an N-terminal substrate binding domain and a C-terminal glycosyltransferase domain.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations

    Jing Xue et al.
    Cryo-EM analysis of human ZnT8 reveals a large conformational change of TMD during the transport cycle.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    An elusive electron shuttle from a facultative anaerobe

    Emily Mevers et al.
    The identification of ACNQ as an extracellular electron shuttle solves a longstanding problem in bacterial physiology and provides new tool for bioenergy development.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Anaerobic Bacteria: Solving a shuttle mystery

    Bridget Conley, Jeffrey Gralnick
    Shewanella oneidensis bacteria use an abiotic reaction to help shuttle electrons outside of the cell.
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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    The presence and absence of periplasmic rings in bacterial flagellar motors correlates with stator type

    Mohammed Kaplan et al.
    A correlation between the periplasmic embellishment of the flagellar motor and its stator system type is described, motors with dual H+-dependent stator systems have one periplasmic ring formed by MotY.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Coincidence detection and bi-directional transmembrane signaling control a bacterial second messenger receptor

    Richard B Cooley et al.
    Building on previous work (Chatterjee et al., 2014), the mechanism of coincidence detection in bacterial second messenger signaling across membranes is revealed at a molecular level, providing insight into the regulation of a conserved transmembrane receptor.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Fluorescent sensors for activity and regulation of the nitrate transceptor CHL1/NRT1.1 and oligopeptide transporters

    Cheng-Hsun Ho, Wolf B Frommer
    Peptide and nitrate transporters have been converted into fluorescent reporters of transport activity and have been used to measure various transport properties including the dual affinity of the nitrate transceptor

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