Fam60a, a component of the Sin3a complex, is required for embryonic development and regulates methylation at a subset of gene promoters.

Endothelial Differentiation Factor 1 (EDF1) plays a critical role in driving mRNA-specific quality control and global transcriptional responses in response to ribosome collisions.

Elimination of GABA_A receptors from the axon terminals of specific retinal bipolar cell types alters the sensitivity and kinetics of retinal output.

The limits to the global distribution of the mosquitoes that transmit dengue and chikungunya have been predicted using a species distribution modelling approach.

Fluctuation of biomarkers is a novel way of studying system stability during stable and unstable states of health and disease, revealing the systems' ability to cope with external perturbations.

The NeuroML model description language, with its extensive software ecosystem, supports researchers in the development of FAIR, data-driven, biologically detailed models of neural systems.

Cells adapt to extracellular hypertonicities using regulatory volume increase (RVI), and TNFR1-mediated NFkB activation is indispensable for RVI, but the increased cytoplasmic macromolecular crowding can inhibit TNFR1 signaling and prevent RVI at severe hypertonicities.

Functional and molecular analyses of two distinct skeletal stem cell populations establish the important role of stem cell diversity that provides a framework for novel investigations into skeletal biology.

Inducing neuronal mitochondrial activity during central nervous system inflammation counteracts inflammation-induced neuronal electron transport chain deficiency and calcium toxicity, thereby protecting against neuronal loss in a multiple sclerosis mouse model.

Heterogeneity in perceptual sensitivity of human cone-mediated vision across wavelength originates in the cone photoreceptors, where S cones exhibit distinct functional properties in comparison to L and M cones.