Single-cell analyses of cells infected by Herpes Simplex Virus 1 revealed extreme heterogeneity among infected cells, including the robust activation of developmental gene programs in highly infected cells.
A curated resource to study the brain RNA expression patterns of the genes that regulate palmitoylation is presented, alongside a detailed exploration of how these patterns can inform future research.
Single-cell transcriptomes of olfactory receptor neurons at multiple developmental stages reveal cell-type-specific gene expression programs that underlie their development and sensory biology.
Single-cell chromatin accessibility analysis reveals the intricate regulatory landscape of mouse testicular development, uncovering novel cell subpopulations and transcription factors, and offering valuable insights into the molecular mechanisms driving germ cell and somatic cell maturation.
KLK10 is a flow-sensitive endothelial protein that serves as an anti-inflammatory, barrier-protective, and anti-atherogenic factor with therapeutic potential.
Identification of bone marrow Adipoq-lineage progenitors as a novel and major cellular source of M-CSF in mice and humans, which controls bone marrow macrophage development, osteoclastogenesis, and bone mass in physiological and pathological conditions.
Ximena Ibarra-Soria, Thiago S Nakahara ... Darren W Logan
The neuronal composition of a mouse’s nose is individually unique due to a combination of olfactory experience and genetic variation local to olfactory receptor genes.
Single-cell transcriptomics correlated with in situ gene expression analysis provide an overview of the diversity and molecular features of cell types in the squid Loligo vulgaris.
Isabella Farhy-Tselnicker, Matthew M Boisvert ... Nicola J Allen
RNA sequencing and genetic mouse models reveal that transcriptional changes to astrocytes in the developing cortex are not intrinsic but influenced by their environment and determine that expression of astrocyte synapse-regulating genes and neuronal synaptogenesis is modulated by ongoing astrocyte-neuron communication.
